CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data
نویسندگان
چکیده
MOTIVATION Recent advances in flow cytometry enable simultaneous single-cell measurement of 30+ surface and intracellular proteins. CytoSPADE is a high-performance implementation of an interface for the Spanning-tree Progression Analysis of Density-normalized Events algorithm for tree-based analysis and visualization of this high-dimensional cytometry data. AVAILABILITY Source code and binaries are freely available at http://cytospade.org and via Bioconductor version 2.10 onwards for Linux, OSX and Windows. CytoSPADE is implemented in R, C++ and Java. CONTACT [email protected] SUPPLEMENTARY INFORMATION Additional documentation available at http://cytospade.org.
منابع مشابه
Numerical and Experimental Investigations for Design of a High Performance Micro-hydro-kinetic Turbine
Design and manufacturing of a high performance micro-hydro-kinetic turbine is discussed in the present paper. The main goal is manufacturing an equipped experimental model of hydro-kinetic turbine with highest energy absorption from water current. A multi-shape ducted turbine comprised of a multi-part diffuser was manufactured that can be converted to many experimental models for studying vario...
متن کاملMethods for regression analysis in high-dimensional data
By evolving science, knowledge and technology, new and precise methods for measuring, collecting and recording information have been innovated, which have resulted in the appearance and development of high-dimensional data. The high-dimensional data set, i.e., a data set in which the number of explanatory variables is much larger than the number of observations, cannot be easily analyzed by ...
متن کاملA new approach for data visualization problem
Data visualization is the process of transforming data, information, and knowledge into visual form, making use of humans’ natural visual capabilities which reveals relationships in data sets that are not evident from the raw data, by using mathematical techniques to reduce the number of dimensions in the data set while preserving the relevant inherent properties. In this paper, we formulated d...
متن کاملAnalysis of High-order Approximations by Spectral Interpolation Applied to One- and Two-dimensional Finite Element Method
The implementation of high-order (spectral) approximations associated with FEM is an approach to overcome the difficulties encountered in the numerical analysis of complex problems. This paper proposes the use of the spectral finite element method, originally developed for computational fluid dynamics problems, to achieve improved solutions for these types of problems. Here, the interpolation n...
متن کاملHigh-Dimensional Unsupervised Active Learning Method
In this work, a hierarchical ensemble of projected clustering algorithm for high-dimensional data is proposed. The basic concept of the algorithm is based on the active learning method (ALM) which is a fuzzy learning scheme, inspired by some behavioral features of human brain functionality. High-dimensional unsupervised active learning method (HUALM) is a clustering algorithm which blurs the da...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Bioinformatics
دوره 28 18 شماره
صفحات -
تاریخ انتشار 2012